羟基磷灰石晶须抗菌改性的工艺研究

›› 2014, Vol. 34 ›› Issue (10): 725-729.

羟基磷灰石晶须抗菌改性的工艺研究

金建烽¹,王刚²,张文云²,陈庆华³,郝爱连¹,刘文英¹

1. 昆明市口腔医院
2. 成都军区昆明总医院口腔科
3. 昆明理工大学材料科学与工程学院

收稿日期:2014-04-08 修回日期:2014-05-05 出版日期:2014-10-28 发布日期:2014-10-15
通讯作者: 张文云 E-mail:wenyunzh@126.com
基金资助:
羟基磷灰石晶须的抗菌改性及机理研究

The study of antibacterial modification of hydroxyapatite whisker

Received:2014-04-08 Revised:2014-05-05 Online:2014-10-28 Published:2014-10-15

摘要/Abstract

摘要： 目的探讨纳米氧化锌（ZnO）在不同pH值和温度下改性-羟基磷灰石晶须（HAPw）的工艺研究。方法在pH=6.4或6.6，温度为37 ℃或70 ℃条件下，醋酸锌溶胶-凝胶法改性羟基磷灰石晶须，经搅拌、超声、旋转、干燥、焙烧得白色粉末，应用透射电镜、扫描电镜和X射线能量色散谱方法分析。结果当pH=6.4，温度为70 ℃时，ZnO-HAPw复合体形貌为颗粒状；当pH=6.6，温度为70 ℃时，ZnO-HAPw复合体形貌为三角形状；当pH=6.6，温度为37 ℃时，ZnO-HAPw复合体形貌为短棒状或锣钉状，X射线能量色散谱方法分析晶须表面复合物为ZnO。结论醋酸锌溶胶-凝胶法可改性羟基磷灰石晶须表面。不同温度和pH值下可形成不同形貌ZnO-HAPw复合体。

关键词: 氧化锌, 羟基磷灰石晶须, 溶胶-凝胶法, 改性, 形貌

Abstract: Objective To explore the preparation of several kinds of morphologies of ZnO HAPw with different temperatures and pH values.Methods Hydroxyapatite whisker was modified by Zinc acetate via solgel,which was stirred,concussed,spun and annealed,and then white powder was obtained.At last,it was analyzed by transmission electron microscopy scanning electron microscope and energy dispersive Xray spectroscopy.Results Four kinds of morphologies of ZnOHAPw were granule,triangle,short rod and gongs nail at pH=6.4 and 70 ℃,pH=6.6 and 70 ℃,pH=6.6 and 37 ℃,pH=6.6 and 37 ℃ respectively.It was demonstrated that the substance on the whisker surface was ZnO by analyzing energy dispersive Xray spectroscopy.Conclusions Hydroxyapatite whisker could be modified by Zinc acetate via solgel.And different morphologies of ZnOHAPw can be produced with different temperatures and pH values.

Key words: Zinc oxide, Hydroxyapatite whisker, Sol-gel method, Modification, Morphology

中图分类号:

R783.1

金建烽王刚张文云陈庆华郝爱连刘文英. 羟基磷灰石晶须抗菌改性的工艺研究[J]. 口腔医学, 2014, 34(10): 725-729.

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