›› 2021, Vol. 41 ›› Issue (3): 265-268.

• 综述 • 上一篇    下一篇

牙龈卟啉单胞菌与不良妊娠结局的相关研究进展

齐帅,林晓萍   

  1. 中国医科大学附属盛京医院
  • 收稿日期:2020-07-20 修回日期:2020-08-10 出版日期:2021-03-28 发布日期:2021-03-28
  • 通讯作者: 林晓萍 E-mail:xiaoping_ba@126.com
  • 作者简介:2020-09-17
  • 基金资助:
    国家自然科学基金;中华口腔医学会专项基金

Advances on correlations between porphyromonas gingivalis and adverse pregnancy outcomes

Shuai QI1,   

  • Received:2020-07-20 Revised:2020-08-10 Online:2021-03-28 Published:2021-03-28

摘要: 龈卟啉单胞菌(Porphyromonas gingivalis, P.gingivalis)是一种革兰阴性厌氧菌,是牙周炎尤其是慢性牙周炎病变区或活动部位最主要的病原菌。研究表明,牙周炎与多种不良妊娠结局(adverse pregnancy outcomes, APO)有关,这一过程涉及多种病理生理机制,而P.gingivalis作为关键牙周致病菌之一在其中扮演重要角色。目前我们对P.gingivalis与APO的关系及其作用机制的认识仍然十分有限。该文拟通过回顾近年来发现的P.gingivalis与APO之间相关的直接或间接的证据,对P.gingivalis与APO的联系和作用机制作一综述。

关键词: 牙周炎, 牙周致病菌, 牙龈卟啉单胞菌, 不良妊娠结局

Abstract: Porphyromonas gingivalis (P. g) is a gram-negative anaerobic bacterium, which is the main pathogen of periodontitis, especially chronic periodontitis. Studies have shown that periodontitis is related to adverse pregnancy outcomes (APO). This process involves a variety of pathophysiological mechanisms, and P. g, as one of the key periodontal pathogens, plays an important role. At present, our understanding of the relationship between P. g and APO and its mechanism of interaction is still limited. This paper intends to review the direct or indirect evidence of the relationship between P. g and APO in recent years, and to make a review of the relationship and mechanism of interaction between P. g and APO.

Key words: Periodontitis, Periodontal pathogens, Porphyromonas gingivalis, Adverse pregnancy outcomes

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