口腔医学 ›› 2026, Vol. 46 ›› Issue (1): 14-19.doi: 10.13591/j.cnki.kqyx.2026.01.003

• 口腔遗传病和罕见病的诊治 • 上一篇    下一篇

多发性特发性牙根吸收的病因与诊疗策略

关业雯, 宋亚玲()   

  1. 武汉大学口腔医(学)院口腔医学湖北省重点实验室,口腔生物医学教育部重点实验室,口颌系统重建与再生全国重点实验室,湖北武汉(430079)
  • 收稿日期:2025-09-29 出版日期:2026-01-28 发布日期:2026-01-16
  • 通讯作者: 宋亚玲 E-mail:sningya@whu.edu.cn
  • 作者简介:宋亚玲,教授,一级主任医师,博士生导师。武汉大学口腔医学院特诊科主任。兼任中华口腔医学会第二届口腔遗传病与罕见病专业委员会主任委员,中华口腔医学会牙体牙髓病学专业委员会常务委员,湖北省口腔医学会常务理事、第四届牙体牙髓病学专业委员会主任委员,武汉市口腔医学会副会长,国家医学考试中心试题开发专家委员会委员。美国宾夕法尼亚大学牙学院访问学者。长期从事牙体牙髓病、口腔遗传病与罕见病的临床、教学和科研工作,主要研究方向为遗传因素与环境因素在牙发育异常疾病中的作用与机制以及牙发育异常相关疾病的早期诊断和综合防治。主持国家自然科学基金、湖北省杰青、中央高校科研专项等多项科研项目。获湖北省科技进步奖二等奖1项(2020年)。发表学术论文70余篇,其中SCI论文40余篇。
  • 基金资助:
    国家自然科学基金(82370912)

Multiple idiopathic root resorption: Etiology and management strategies

GUAN Yewen, SONG Yaling()   

  1. State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine, Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2025-09-29 Online:2026-01-28 Published:2026-01-16
  • Contact: SONG Yaling E-mail:sningya@whu.edu.cn

摘要:

多发性特发性牙根吸收是罕见的呈进行性发展的牙体破坏性疾病,累及全口至少3颗牙,其病因、发病机制尚不明确,根据吸收发生部位的不同分为多发性特发性牙颈部吸收、多发性特发性根尖吸收和多发性特发性牙内吸收。多发性特发性牙颈部吸收是发生于牙齿颈部近釉牙骨质界部位的进行性外吸收,早期可无明显临床表现,短时间内吸收范围迅速扩大,进而出现咬合疼痛、牙松动甚至脱落。多发性特发性根尖吸收是发生于牙根尖的进行性外吸收,通常无明显临床症状,晚期可出现松动度增加。多发性特发性牙内吸收是发生于牙齿内部的进行性吸收,早期也常无明显症状,伴随着吸收进展而出现牙变色等症状。近年来,国内外对这类疾病的关注逐渐增加。本文将从疾病的定义、病因、诊断、治疗、预后等方面进行综述,以期为临床诊疗提供参考。

关键词: 多发性, 特发性, 牙颈部吸收, 根尖吸收, 牙内吸收

Abstract:

Multiple idiopathic root resorption(MIRR) is a rare progressive destructive dental condition with unclear etiology and pathogenesis. Based on anatomical location, it can be classified into three types: multiple idiopathic cervical root resorption(MICRR), multiple idiopathic apical root resorption(MIARR), and multiple idiopathic internal root resorption(MIIRR). MICRR is characterized by progressive external resorption at the cervical region near the cementoenamel junction, affecting at least three teeth in the dentition. While often asymptomatic initially, it can progress rapidly, leading to occlusal pain, tooth mobility, and eventual tooth loss. MIARR presents as progressive external resorption at the root apex, also involving a minimum of three teeth. This condition typically remains clinically silent until late stages when increased tooth mobility may occur. MIIRR involves progressive internal resorption within the tooth structure, as well as affecting at least three teeth. Early stages are frequently asymptomatic, with tooth discoloration appearing as the condition advances. In recent years, there has been growing international attention to these conditions. This article comprehensively examines their definitions, etiology, diagnostic criteria, treatment approaches, and prognostic outcomes, aiming to provide valuable clinical references for dental practitioners.

Key words: multiple, idiopathic, cervical resorption, apical resorption, internal resorption

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