口腔医学 ›› 2026, Vol. 46 ›› Issue (3): 230-235.doi: 10.13591/j.cnki.kqyx.2026.03.012

• 综述 • 上一篇    下一篇

牙周-牙髓联合病变预后影响因素的研究进展

周帅, 王艺翔, 刘书欣, 李晓军()   

  1. 浙江大学医学院附属口腔医院牙周病科, 浙江大学口腔医学院,浙江省口腔疾病临床医学研究中心,全省口腔生物医学重点实验室, 浙江杭州 (310000)
  • 收稿日期:2025-05-12 出版日期:2026-03-28 发布日期:2026-03-31
  • 通讯作者: 李晓军 E-mail:ddslee312@zju.edu.cn
  • 基金资助:
    国家重点研发计划(2023YFC2506303);浙江省科技重点研发计划(2024C03241);浙江省教育厅(Y202250043);浙江大学医学院附属口腔医院探索与研发项目(RD2022DXKB03)

Progress of prognostic factors of endo-periodontal lesion

ZHOU Shuai, WANG Yixiang, LIU Shuxin, LI Xiaojun()   

  1. Department of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Zhejiang Key Laboratory of Oral Biomedical, Hangzhou 310000, China
  • Received:2025-05-12 Online:2026-03-28 Published:2026-03-31

摘要:

牙周-牙髓联合病变(endo-periodontal lesion,EPL)同时累及牙周与牙髓组织,导致患牙的预后较难确定,给临床实践带来了巨大挑战。2018年牙周病和植体周病国际研讨会提出了EPL新分类标准,本文从EPL新分类出发,以牙根损伤、全口牙周状况及病变范围为核心,结合解剖异常(畸形根面沟、复杂根管系统)、全身因素(糖尿病、吸烟)、牙列状况及社会心理因素等方面,通过总结近年来相关研究,系统梳理影响EPL患牙预后的多种因素,以期为临床医生在EPL患牙的诊疗决策中提供科学依据与实践指导。

关键词: 牙周-牙髓联合病变, 预后影响因素, 牙根损伤, 解剖异常

Abstract:

Endo-periodontal lesion (EPL) involves both periodontal and pulpal tissues, often leading to a difficult-to-determine prognosis for the affected tooth and posing significant challenges to clinical practice. The 2018 World Workshop on Periodontal and Peri-implant Diseases and Conditions proposed a new classification standard for EPL. This article starts from the new EPL classification, centers on root damage, full-mouth periodontal condition, and lesion extent, and systematically reviews multiple prognostic factors for EPL-affected teeth by integrating aspects such as anatomical abnormalities (palatogingival grooves, complex root canal systems), systemic factors (diabetes, smoking), dentition condition, and sociopsychological factors. By summarizing recent research, it aims to provide scientific evidence and practical guidance for clinicians in making diagnostic and therapeutic decisions regarding EPL-affected teeth.

Key words: endo-periodontal lesion, prognostic factors, root damage, anatomical abnormalities

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