牙髓再生相关细胞因子研究进展

doi:10.13591/j.cnki.kqyx.2023.03.018

摘要/Abstract

摘要：

随着分子生物学、生物材料学、组织工程学等学科的不断发展,牙髓根尖周病的再生性治疗面临新的机遇。目前,大量关于牙髓再生的研究表明:细胞因子在促进牙髓干细胞迁移、增殖和成骨向分化等方面发挥重要作用。该文将对近期作为热点研究的几类牙髓再生的相关细胞因子进行综述,分析其在牙髓再生中的作用及调节机制。

关键词: 牙髓再生, 血管生成, 细胞因子, 信号分子, 信号通路, SDF-1, CXCL-12, 轴, CXCR4, 浓缩生长因子

Abstract:

With the development of molecular biology, biomaterials and tissue engineering, regenerative treatment of pulpal and periradicular diseases is facing new opportunities. At present, a large number of studies on dental pulp regeneration reveal that cytokines are essential for promoting migration, proliferation and osteogenic differentiation of dental pulp stem cells. In this paper, we review several kinds of cytokines related to dental pulp regeneration, and analyze their roles and regulatory mechanisms in dental pulp regeneration.

Key words: dental pulp regeneration, angiogenesis, cytokines, signal molecule, signaling pathway, SDF-1, CXCL-12, axis, CXCR4, concentrated growth factor

中图分类号:

R349.51

姚敏慧, 吴锦涛, 周愉, 褚凤清, 蒋葭葭, 陈玥, 周莉丽, 李泽汉. 牙髓再生相关细胞因子研究进展[J]. 口腔医学, 2023, 43(3): 282-288.

YAO Minhui, WU Jintao, ZHOU Yu, CHU Fengqing, JIANG Jiajia, CHEN Yue, ZHOU Lili, LI Zehan. Advances in the study on cytokines related to dental pulp regeneration[J]. Stomatology, 2023, 43(3): 282-288.

图/表 1

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