Stomatology ›› 2022, Vol. 42 ›› Issue (4): 354-357.doi: 10.13591/j.cnki.kqyx.2022.04.014

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Application progress of optogenetics technology in stomatology

FU Mengdie, ZHU Danji, YANG Guoli, JIANG Zhiwei   

  1. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China
  • Revised:2021-09-14 Published:2022-04-28

Abstract: Optogenetics technology refers to a technology that uses photosensitive proteins of high spatial-temporal specificity to optically control specific genes. Optogenetics technology has been widely used application in researches of clinical treatment targeted at cardiovascular diseases, visual and auditory disorders, metabolic diseases and neurological diseases. Moreover, it has developed into a hotspot technology in fundamental medical researches. Recently, applications of optogenetics technology in the field of stomatology have been gradually increasing, such as the study of taste system, the treatment of trigeminal neuralgia, the study of maxillofacial muscle innervation, etc. This article reviews applications of optogenetics in stomatology.

Key words: optogenetics, taste system, trigeminal neuralgia, maxillofacial muscle movement, stomatology

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