Stomatology ›› 2022, Vol. 42 ›› Issue (10): 865-868.doi: 10.13591/j.cnki.kqyx.2022.10.001

• Basic Research •     Next Articles

Effects of myricetin on dentin remineralization and bonding strength

WANG Beibei, HAN Fei, YUAN Xiaojun, CHEN Chen, XIE Haifeng   

  1. Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University; Department of Prosthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China
  • Revised:2022-07-07 Online:2022-10-28 Published:2022-10-28

Abstract: Objective To evaluate the remineralization effect of myricetin (MYR) on demineralized dentin matrix and its effect on dentin bonding strength. Methods The middle dentin slices were obtained and then were wet polished with 600 mesh silicon carbides and paper to simulate the smear layer. The dentin slices were etched with 35% phosphoric acid and divided into three groups, which were respectively immersed in distilled water, directly remineralized for 2 d and pretreated with MYR for 30 min and then remineralized for 2 d. Surface morphology of the dentin slices was observed with scanning electron microscope(SEM), and surface materials were analyzed with X-ray diffraction(XRD)and attenuated total reflection Fourier transform infrared spectroscopy(ATR-FTIR). Micro tensile strength (μTBS)and nano-leakage experiments were used to observe the bonding effect. Results SEM showed that the dentin after remineralization could form crystals, while crystals formed by remineralized dentin after MYR pretreatment were the most obvious. XRD and ATR-FTIR analysis revealed that the newly formed crystal was hydroxyapatite(HA). μTBS and nanoleakage experiments showed that remineralization after MYR pretreatment could significantly increase bond strength and reduce nanoleakage. Conclusion MYR pretreatment can promote the remineralization process of demineralized dentin and improve the resin/dentin bonding strength.

Key words: dentin, myricetin, remineralization, hydroxyapatite, bonding

CLC Number: