人工合成抗菌肽在龋病防治中的研究进展

doi:10.13591/j.cnki.kqyx.2022.12.015

Abstract

Abstract: Antimicrobial peptides have strong antibacterial effects and are considered as a potential alternative to traditional antibiotics due to their unique bactericidal mechanism. Compared with natural antimicrobial peptides, synthetic antimicrobial peptides have better antibacterial activity and stability, and can be used for dental caries prevention and treatment in terms of inhibiting major cariogenic bacteria, reducing the formation of dental plaque biofilm, and promoting remineralization. This paper will review these synthetic antimicrobial peptides and their mechanisms, and provide a reference for further study on synthetic antimicrobial peptides in caries prevention and treatment.

Key words: synthetic antimicrobial peptide, dental caries, Streptococcus mutans, biofilm, tooth remineralization

CLC Number:

R781.1

YUAN Wenjin, HAN Jiaqi, YANG Jie, DONG Ning, JIANG Qiu. Research progress of synthetic antimicrobial peptides in prevention and treatment of dental caries[J]. Stomatology, 2022, 42(12): 1129-1133.

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Research progress of synthetic antimicrobial peptides in prevention and treatment of dental caries

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