Stomatology ›› 2023, Vol. 43 ›› Issue (1): 92-96.doi: 10.13591/j.cnki.kqyx.2023.01.016

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Progress of research on chitosan-based microspheres in oral tissue lesions

ZHOU Huajun1,DING Yude2,YANG Fan2()   

  1. School of Stomatology, Zhejiang Chinese Medical University, Hangzhou 310053,China
  • Revised:2022-04-19 Online:2023-01-28 Published:2023-01-11
  • Contact: YANG Fan E-mail:dr_fanyang@163.com

Abstract:

Chitosan-based microspheres use chitosan as the main material to obtain particles with special structures through microsphere processing technology. They have the ability of slow and controlled release of drugs and the role of scaffolding, which have great application prospect in stomatology, but the application of chitosan-based microspheres is still in the research stage and has not yet been applied in clinical practice. This article reviews progress of domestic and foreign research on chitosan-based microspheres, in aspects of treatment of oral and jawbone tissue defects, periodontal diseases, dental pulp diseases and nerve tissue injury, in order to provide reference for follow-up research.

Key words: chitosan-based microsphere, drug loading, sustained release, oral tissue

CLC Number: