Abstract:

Biomaterials have been the focus of research and innovation in medical materials in recent years. They are natural or synthetic materials that can contact and interact with human cells, tissues and organs to obtain diagnostic, restorative or therapeutic effects. In stomatology, biomaterials have received high attention, such as applications in implant restorations, pulp regeneration, periodontal tissue regeneration and other frontier fields. Dentine hypersensitivity is manifested as short and sharp pain from stimulus to exposed dentin, which has high prevalence and seriously affects people's daily life. However, the pathogenesis is still controversial and traditional treatment is ineffective. Recently, various biomaterials have been invented to treat dentine hypersensitivity. This paper reviews the innovative development of biomaterials in the treatment of dentine hypersensitivity and highlights the ionic mechanism. It is expected that biomaterials can provide new models and ideas for exploring the pathogenesis and therapies of oral diseases.

Key words: biomaterials, dentine hypersensitivity, oral diseases treatment, ionic mechanism