Abstract:

Objective To analyze the correlation among periodontitis, oral and gastric Helicobacter pylori by investigating the infection of Helicobacter pylori and periodontal status in 127 patients. Methods From December 2021 to June 2022, 127 cases of patients who were tested for gastric Helicobacter pylori by 14C-urea breath test in Nantong Hospital of Traditional Chinese Medicine or The third People's Hospital of Nantong, were included to fill out the questionnaire and tested for oral Helicobacter pylori and periodontal examination, according to the inclusion and exclusion criteria and following the principle of voluntary participation. Statistical SPSS 20.0 software was used to analyze the data. Results Oral and gastric Helicobacter pylori infections were correlated in 127 patients (P<0.05). Oral Helicobacter pylori infection was also associated with periodontal status (P<0.05). The infection rate of gastric Helicobacter pylori in patients with moderate to severe periodontitis tended to increase, but the difference was not statistically significant (P>0.05). Multivariate Logistic regression analysis of the total population suggested that oral Helicobacter pylori was a risk factor for gastric Helicobacter pylori infection. Conclusion The infection rate of oral Helicobacter pylori is closely related to the infection rate of gastric Helicobacter pylori. Moderate to severe periodontitis can increase the infection rate of Helicobacter pylori.

Key words: oral Helicobacter pylori, gastric Helicobacter pylori, moderate to severe periodontitis, correlation