衰老细胞和骨相关疾病关系的研究进展

doi:10.13591/j.cnki.kqyx.2025.02.010

Abstract

Abstract:

Bone-related diseases are a group of inflammatory diseases characterized by abnormal bone resorption and formation, with a wide variety of diseases involving age, inflammation, obesity, genetics, radiation, and other pathogenic factors. In recent years, senescent cells have become an important mechanism for age-related diseases, and their role in bone-related diseases has attracted the attention of researchers. Senescent cells are gradually being used as therapeutic targets for bone-related diseases. In this paper, we present a review of the mechanism of senescent cells in various types of bone-related diseases, which will provide new strategies for the prevention and treatment of bone diseases.

Key words: senescent cells, senescence-associated secretory phenotype, bone diseases

CLC Number:

R714.257

TANG Jinru, LI Bo, LIU Yunkun, HOU Zeyu, LI Longjiang. Role of senescent cells in bone-related diseases: An updated review[J]. Stomatology, 2025, 45(2): 134-138.

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Role of senescent cells in bone-related diseases: An updated review

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