Abstract: Objective Semi-anatomic (20°) artificial teeth complete denture and non-anatomic (0°) artificial teeth complete denture were the common methods to repair the upper and lower dentition defect. We will observe and compare the masticatory function of the two types of complete denture. Methods 7（5 males&2 females） volunteered edentulous patients about 68.7 years old on average were selected for our study and two complete dentures of the same base, but different Posterior cusp inclinations (20°, 0°) were designed. The masticatory efficiency was measured by the Absorbance method on the day when patients wore the denture and the myoelectric manifestations of TA and MM were scanned after that. Results The mean masticatory efficiency of 0°complete denture is lower than 20°complete denture (P<0.05). The EMG activity of 0° group was more active than the 20° group when chewing peanut (P<0.05). The masticatory efficiency was in proportion to the TA, MM EMG activity. Conclusions When chewing food with certain hardness, better masticatory efficiency can be achieved with 20°complete denture and the work of the masticatory muscles can be easier.