Abstract: Objective To explore the clinical mechanism of application of miniscrew implant anchorageassisted correction for adult Class Ⅱ Division 2 malocclusion. Methods Twelve cases of Class Ⅱ Division 2 malocclusion patients were selected,including 4 male patients and 8 female patients,aging from 18 to 38 years old,with an average age of 21.0 years old.Miniscrew implant anchorages were applied to help the whole upper dentition move backwards and control anterior teeth intrusion.The changes of patients' teeth,hard and soft tissues before and after treatment were analyzed. Results The dental crown of maxillary central incisor in sagittal direction kept still basically,the tooth root moved 3.63 mm on average with tipping ratio of 6050% and anterior teeth intrusion of 4.60 mm.The crown of maxillary first premolar moved 3.25 mm,the tooth root 3.65 mm with the average tipping ratio of 112.3% and the crown of tooth was intruded for 2.90 mm.The crown of maxillary first molar was distalized for 3.11 mm,the tooth root was distalized for 3.21 mm,with average tipping ratio of 103.2% and the crown of tooth was intruded for 1.17 mm.The crown of maxillary second molar has moved 3.22 mm,and the tooth root was distalized for 3.15 mm averagely,with average tipping ratio of 97.8%,being intruded for 0.69 mm. Conclusions The application of miniscrew implant anchorage is effective for group distal movement of maxillary dentition,anterior teeth intrusion and the reconstruction of the maxillary anterior alveolar bone.It is an effective way of nontooth extraction correction for Class Ⅱ Division 2 malocclusion cases.