Abstract: Objective　To evaluate the clinical effect of Er,Cr:YSGG laser on soft tissue surgery. Methods　Twenty-nine cases were treated by Er,Cr:YSGG laser on soft tissue surgery without local anesthesia and sutures required. The effect after Er,Cr:YSGG laser treatment was evaluated. Results　After laser therapy without other special treatment，there was no pain，no bleeding except one epulis，and there was no infection．Wound healed after five to seven days except one epulis，without obvious scars. Conclusion　Er,Cr:YSGG laser provides a more efficient, secure, convenient, and comfortable treatment.