Abstract: Objective To assess the perceptions of patients, parents, and orthodontists of white spot lesions during orthodontic treatment. Methods A questionaire survey of the perceptions of orthodontic patients (n＝ 247), parents (n ＝ 223), and orthodontists (n ＝ 51) was carried out, and then the results were analyzed. Results Three groups all thought that white spot lesions reduced the aesthetic of teeth, and that the major responsibility for the occurrence of white spot lesions was on the patients（P＜0.01）. The main reasons of white spots were incorrect way of brushing teeth or insufficient time or times of brushing teeth. Conclusions Patients, patients’ parents, and orthodontists all believed that white spot lesions reduced the aesthetic of teeth, and that the major responsibility for the occurrence of white spot lesions was on the patients.