Abstract: Regenerative endodontics, with the development of biologically based treatment modalities, includes methods used to replace diseased dental pulp or to allow complete formation of a dental pulplike tissue, to maintain the normal function of dental pulp. Today, the major treatment in regenerative endodontics appears to use oral or periapical derived stem cells to create microenvironment to facilitate pulp repair or regeneration, some novel procedures like pulp revascularization or cell homing regeneration were performed to treat immature permanent teeth with pulp necrosis, which provides many research materials and available treatment methods for the regeneration of dental pulp. The purpose of this article is to review the current situation and prospects of regenerative endodontics.

Key words: immature permanent teeth, regenerative endodontics, stem cell, revascularization