茶黄素预防龋病的动物实验

Abstract

Abstract: Objective Through the animal experiment to observe the effectiveness of TFs on the prevention of the dental caries. Methods Twentyfour 23-dayold SD rats were divided randomly into three groups (TFs、NaF、H2O), 8 rats per group, half male and half female. All the rats were inoculated with S.mutans and fed with cariesinducing diet 2000 and the 5% sugar water, and then rats’ were rinsed with the MIC purity TFs、250 mg/L NaF solution and distilled water separately. After 5 weeks’ sequential processing execution, rats were sacrificed for scoring caries molar teeth by Keyes' method, and the rats’ molar caries situation was evaluated. Finally, the data collected were analyzed with SPSS 22.0 version. Results The Keyes scores showed rats under TFs appeared different degrees of caries’ lesion, and it had reduced the prevalence rates of dental smooth surface caries by 85.0% and sulcal surface dentine caries by 62.5%. Conclusions The TFs in MIC has an obvious inhibitory effect on the dentine caries of rats.

Key words: dental caries, Theaflavins, model animal, S.mutans

CLC Number:

R781.1

References

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Effects of TFs on caries’ development in rats

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