Abstract: Objective To evaluate the efficacy of the autogenous dentin particles combining PRF in treating class Ⅱ furcation involvement. Methods 32 patients without systemic disease but with mandibular first molar class Ⅱ furcation involvement, who had been treated through initial therapy were selected. In the experiment group, 16 patients with 16 teeth, the autogenous dentin particles and PRF were placed in the areas with furcation defect, while in the control group, another 16 patients with 16 teeth, Bio-Oss and collagen membrane were used. The patients were followed up at 3,6,12 months after operation. The efficacy was evaluated with clinical parameters and X-ray examination. Results The following periodontal indexes including PD,AL,HPD significantly decreased in both groups after operation(P＜0.05) The alveolar bone density obviously increased in two groups(P＜0.05). Conclusion The clinical effect of the treatment on class Ⅱ furcation involvement by autogenous dentin particles with PRF is remarkable.

Key words: autogenous dentin particular, PRF, class Ⅱ furcation involvement