Abstract: Abstract: Objective To analyze the effect of basic treatment, orthodontics and prosthodontic treatment on the aesthetic reconstruction of gingival papilla of the incisor area in patients with periodontal disease. Methods 31 cases of patients with deep overbite and periodontal disease caused by previous bad repair were selected, and they were treated with a comprehensive method composed of basic treatment, orthodontics and prosthodontic treatment. Changes of the related indexes of the gingival papilla were observed before and after treatment. Results After basic treatment, PD, GI, PLI, SBI, and GAL in patients were significantly lower before treatment (P<0.05). At the moment when orthodontics was completed, and six months after prosthodontic treatment, PD, GI, PLI, SBI, and GAL in patients were also significantly lower before treatment (P<0.05), but the difference was not statistically significant compared to the changes of indexes after basic treatment (P>0.05). After 6 months of prosthodontic treatment, the distribution of the gingival papilla index was significantly better than that at the moment when the treatment was completed (Z=-4.327, P<0.001). After 6 months of treatment, the value of PH in patients was significantly higher than that at the moment when the treatment was completed and the difference was statistically significant (P<0.05). Conclusion The treatment of periodontal disease with the combination of basic treatment, orthodontic treatment and prosthodontic treatment has good curative effect, which can significantly improve the patients' anterior dental aesthetics.

Key words: Periodontal disease, orthodontic, restoration, tooth area, gingival papilla