›› 2017, Vol. 37 ›› Issue (5): 453-456.

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Effect and mechanism of nano-hydroxyapatite on bone regeneration

  

  • Received:2016-11-16 Revised:2016-12-07 Online:2017-05-28 Published:2017-05-19

Abstract: Due to chemical similarity of nano-hydroxyapatite (nano-HAP) to inorganic component of bone matrix, nano-HAP and its composites have attracted particular attention in the field of regenerative medicine. However, our understanding of the effect and mechanism of nano-HAP on bone regeneration is still fragmentary. In addition, very little is known about the interaction of nano-hydroxyapatite with the body with regards to its toxicity. In this article, the application, mechanism and biological safety of nano-HAP in bone repair will be reviewed.

Key words: nanophase hydroxyapatite, bone regeneration, mechanism, biological safety

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