›› 2017, Vol. 37 ›› Issue (7): 632-634.

• Clinical Research • Previous Articles     Next Articles

Efficacy observation of rhEGF with hydroxychloroquine tablets in treating erosive oral lichen planus

Hui-Ping CHENG 2   

  • Received:2016-03-22 Revised:2016-07-25 Online:2017-07-28 Published:2017-07-18
  • Contact: Hui-Ping CHENG E-mail:doctor_liuliu@126.com

Abstract: Abstract: Objective To evaluate the clinical effect of rhECF’s with hydroxychloroquine tablets (Plaquenil) on erosion oral lichen planus. Methods 60 cases with erosive oral lichen planus were chosen and randomly divided into two groups. The experimental group included 30 cases which were treated with rhEGF and Plaquenil. The other were in the control group treated with Plaquenil only. All the cases were treated for 3 months and had the subsequent visit after 3-month drug withdrawal The curative effects of the two groups were evaluated according to Level 3 curative standard and then compared. Results The total effective rates of experimental group and control group were 93.3%and 33.3% in three months(P<0.05), 91.23% and 73.63% were the effective rates of subsequent visit after three months(P<0.05).Conclusion The rhEGF with Plaquenil shows better therapeutic response compared with Plaquenilin in subjects with oral lichen planus.

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