Abstract: Periostin(POSTN), also known as osteoblast-specific factor 2 (OSF-2), is found in periosteum and periodontal ligament. It is a kind of extracellular matrix protein that is tissuely integral and essential during maturation, expressed in collagen-enriched fibrous and connective tissue when under constant mechanical stress. At present, studies have shown that Periostin has huge effect on bones;teeth and heart development. In this paper, preliminary studies of the role Periostin plays in the fibroblast expression of human’s periodontal ligament stem cell were reviewed.

Key words: Periostin, Periodontal ligament, Stem cells, Fibroblast