肿瘤坏死因子-α在正畸牙移动中作用的研究进展

Abstract

Abstract: Tumor necrosis factor-α is a monocyte factor involved in the inflammatory response in vivo and can promote osteoclast formation under the combined action of Receptor activator for Nuclear Factor-κ B Ligand.Orthodontic tooth movement is the process of periodontal tissue and bone remodeling under mechanical stress, which requires osteoclast and osteoblast and other periodontal factors. During orthodontic treatment, under the influence of orthodontic force, periodontal tissue will be in a state of mild inflammation, and various inflammatory factors produced can promote periodontal tissue remodeling. Tumor necrosis factor-α plays an important role in orthodontic tooth movement and can promote osteoclast formation, and also has some effects on the formation of osteoblasts. This review summarizes the progress in the study of the role of TNF-α in orthodontic tooth movement.

Key words: Tumor necrosis factor-α , tooth movement, osteoclast, orthodontic force

CLC Number:

R780.2

References

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Research progress of tumor necrosis factor-α in orthodontic tooth movement

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