Abstract: Abstract: Objective To investigate the occurrence of the sharp injuries in tertiary stomatological hospital, and to provide reference for the prevention, protection, and intervention measures of sharp injuries for medical staffs in Jiangsu Provincial Stomatological Hospital. Methods Stratified random sampling was carried out in medical staffs in Jiangsu Provincial Stomatological Hospital accoding to work types to do questionnaire survey about the incidence of sharp injuries in the last year. Results 167 medical workers were investigated, of which 65.9% had experienced sharp injuries in the past year. The frequency of the injuries was 1.92 times per person per year. 62.3% of the respondents had ever attended related training, and only 23.3% of the injured respondents reported their sharp injuries. In the case of known sources of exposure, the exposure to blood-borned diseases was 7.7%. The nurses were most likely ito suffer from sharp injuries (77.2%). The operating room and supply room were ranked as the highest risk department for sharp injuries. “Operation suture” and “root canal therapy” were the highest risk actions for sharp injuries among doctors, while “needle heads and passing sharp instruments” are most risky for nurses. Conclusion Sharp injuries are common occupational injuries for stomatological staffs. Measures should be taken to reduce the incidence rate of sharp injury like reducing unnecessary medical practices, changing incorrect habits and behaviors, strengthening occupational training, carrying out standard precautions.