›› 2014, Vol. 34 ›› Issue (8): 570-572.

• Basic and Clinical Research • Previous Articles     Next Articles

Cytokeratin expression in cervical lymph nodes of patients with squamous cell carcinoma of the gingival

  

  • Received:2013-12-17 Revised:2014-02-21 Online:2014-08-28 Published:2014-09-25
  • Contact: Kun YUE E-mail:skyspace1128@163.com

Abstract: Objective  To study the expression of cytokeratin in cervical lymph nodes of patients with squamous cell carcinoma of the gingival .Methods: Immunohistochemical examination with pan-cytokeratin (CK-AE1/AE3) was performed on 28 positive lymph nodes and 139 negative lymph nodes that were from 17 patients with squamous cell carcinoma of gingival.Results:28 lymph nodes with metastasis shown by general pathological examination (HE stain) were positive for CK. 11 lymph nodes(in 9 patients) that were shown to have no metastasis by general examination were also positive for CK and 6 nodes were found in level Ⅰand 5 nodes were found in level Ⅱ.Conclusion: The immynohistochemical with pan-cytokeratin (CK-AE1/AE3) is a good method of detecting lymph node micrometastasis in squamous cell carcinoma of the gingival.

Key words: cytokeratin, gingival, lymph nodes, micrometastasis