Abstract: Abstract: Objective By compounding and testing nHA/Mg/chitosan coating, to explore the preparation of a high-quality biodegradable scaffold materials. Methods The nHA/Mg composites were synthesized by powder metallurgy. With ammonium bicarbonate as pore-forming agent, chitosan coating was prepared by immersion method on the surface of nHA/Mg alloy. The composite surface, the morphological structure of cross section, and the surface morphology changed after being soaked in simulated body fluid corrosion were observed by SEM. Results The average porosity of nHA/Mg alloy was 50%, and the pore diameter was 50~120μm. Ammonium bicarbonate was the suitable pore-forming agent, and chitosan coating could significantly improve the material degradation time and PH value, slowing down the corrosion rate of the magnesium alloy. Conclusion The composite material nHA/Mg/chitosan coating was a biodegradable scaffold with porous structure and good corrosion resistance.

Key words: Scaffold materials, Magnesium, nano-hydroxyapatite, Chitosan coating