Stomatology ›› 2023, Vol. 43 ›› Issue (5): 465-470.doi: 10.13591/j.cnki.kqyx.2023.05.014

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Advances in the regulation of immune cells in jaw homeostasis and damage repair

ZHONG Jiawei1,PAN Jian1,2,GUO Yuchen1,2()   

  1. West China School of Stomatology Sichuan University, Chengdu 610000, China
  • Revised:2022-10-26 Online:2023-05-28 Published:2023-05-31
  • Contact: GUO Yuchen E-mail:guoyuchen@scu.edu.cn

Abstract:

The jaw is constantly renewed and remodeled throughout the lifetime and is a crucial part of the stomatognathic system. The jaw homeostasis and repair of jaw injury are regulated by multiple cells and molecules, in which immune cells play an important role. Numerous studies have confirmed that the immune system could regulate the process of bone homeostasis and bone remodeling by direct and indirect pathways. This review summarizes the mechanisms of immune cells regulating bone homeostasis and bone reconstruction in order to provide ideas for future in-depth research.

Key words: jaw homeostasis, jaw reconstruction, bone immunity, osteoblast, osteoclast

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