›› 2020, Vol. 40 ›› Issue (11): 1030-1036.

• 综述 • 上一篇    下一篇

根管封闭剂对粪肠球菌抗菌作用的研究进展

刘瑾1,程小刚2,仇珺1,梅笑寒1,白玉1,程庚1,余擎3   

  1. 1. 第四军医大学口腔医院
    2. 中国人民解放军第四军医大学口腔医院
    3. 军事口腔医学重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔医学重点实验室,第四军医大学口腔医院牙体牙髓病科军
  • 收稿日期:2020-03-03 修回日期:2020-04-14 出版日期:2020-11-28 发布日期:2020-11-24
  • 通讯作者: 余擎 E-mail:yuqing@fmmu.edu.cn
  • 基金资助:
    釉基质蛋白纳米微球缓释系统协同根尖区干细胞群促进根尖再生的作 用机制研究;耐低氧粪肠球菌临床分离株生物膜形成、功能及其相关分子机制的研 究;季铵盐化二氧化硅生物玻璃对粪肠球菌临床分离株的杀灭作用及抑制 其粘附过程的机制研究;CAD/CAM 全瓷嵌体修复无髓后牙的基础与临床研究;季铵盐化二氧化硅生物玻璃对粪肠球菌生物膜的杀灭作用及其相关机制研究

Research progress of the antibacterial effect of endodontic sealers on Enterococcus faecalis

  • Received:2020-03-03 Revised:2020-04-14 Online:2020-11-28 Published:2020-11-24

摘要: 细菌及其代谢产物是牙髓病和根尖周病的主要病因之一,根管治疗术是其当前最有效的治疗方法。根管治疗失败的主要原因是根管系统再感染的发生,粪肠球菌是最主要的致病菌之一。根管封闭剂的抗菌作用对防止根管系统再感染的发生具有重要作用,可以提高根管治疗的长期成功率。目前应用于临床的根管封闭剂种类繁多,本文将就各类根管封闭剂对粪肠球菌抗菌作用的研究进展作一综述,这将具备重要的临床指导意义。

关键词: 根管封闭剂, 粪肠球菌, 抗菌作用, 研究进展

Abstract: Bacteria and their by-products are one of the most important causes for pulpal and periapical diseases, and root canal treatment is currently the most effective solution for their treatment. The main reason of the failure of root canal treatment is the occurrence of reinfection within the root canal system, and Enterococcus faecalis (E. faecalis) is one of the major pathogens. The antibacterial effect of endodontic sealers plays an important role in preventing reinfection to the root canal system, which can improve the long-term success rate of root canal treatment. Presently, various of endodontic sealers are available clinically, and the objective of this review was to summarize the antibacterial effects of different endodontic sealers on E. faecalis, which will provide significant evidence for the clinical application of endodontic sealers in root canal treatment.

Key words: endodontic sealer, Enterococcus faecalis, antibacterial effect, research progress

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