口腔医学 ›› 2022, Vol. 42 ›› Issue (12): 1134-1139.doi: 10.13591/j.cnki.kqyx.2022.12.016

• 综述 • 上一篇    下一篇

浓缩生长因子在美学区种植的应用及机制研究进展

孙吉宇, 张曦丹, 朱卓立, 陈晨峰, 杨阳, 甘雪琦   

  1. 口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医院住院医师规范化培训基地——口腔修复基地,四川成都(610041)
  • 收稿日期:2022-02-18 出版日期:2022-12-28 发布日期:2022-12-28
  • 通讯作者: 甘雪琦 E-mail: xueqigan@scu.edu.cn

Research and clinical application progress of concentrated growth factor in the implantology of aesthetic area

SUN Jiyu, ZHANG Xidan, ZHU Zhuoli, CHEN Chenfeng, YANG Yang, GAN Xueqi   

  1. State Key Laboratory of Oral Diseases; National Clinical Research Center for Oral Diseases & Resident Standardization Training Base of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-02-18 Online:2022-12-28 Published:2022-12-28

摘要: 美学区种植修复的功能状态和美学效果的长期稳定是当前的研究热点。浓缩生长因子(concentrated growth factor, CGF)作为第三代血小板浓缩物,因其制备过程简单、无需添加制剂、富含多种生长因子,表现出强大的促进组织修复和再生的能力,正广泛地应用于再生领域。该文将介绍CGF的制备方法、性能特点,并对其促进组织再生的机制研究和应用于美学区种植修复领域的进展作一综述。

关键词: 浓缩生长因子, 种植, 骨缺损, 软组织增量, 美学区

Abstract: The stable aesthetic outcome and functional restoration in the long run become the focus of recent studies on implant in the aesthetic area. Concentrated growth factor (CGF), as a third-generation platelet concentrate product, has been effective in promoting the natural processes of tissue regeneration with simple preparation method, higher multitude of growth factors contained, and no need of any additives. The article will introduce the preparation method, performance characteristics of CGF, and summarize the progress of research on its ability and underlying machanism to promote tissue regeneration and clinical application in implant restoration in aesthetic areas.

Key words: concentrated growth factor, implant, bone defect, soft tissue augmentation, aesthetic area

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