Abstract: Objective To analyze the relationship between the masticatory efficiency and the two modified dentures (long centric occlusal denture and lingualized occlusal denture) of the patients with normal and high amount of biochemical markers of bone turnover, and to provide the reference for how to choose the complete dentures during clinical practice. Methods 85 elderly edentulous patients (45 males and 40 females) with severe residual alveolar ridge resorption were randomly divided to be repaired by long centric occlusal denture or lingualized occlusal denture. The serum amount of biochemical markers of bone turnover (P1NP and CTX) was detected by electrochemiluminescence immunoassay and the patients were divided into the normal group and the higher group. Three months after the complete dentures wearing, masticatory efficiency was determinated by spectrophotometry. Then multifactor analysis of variance was used to analyze the relationship between the masticatory efficiency and the two modified dentitions of the patients with normal and high amount of biochemical markers of bone turnover. Results In the normal group, there was no significant difference in masticatory efficiency between two kinds of dentures(P >0.05). In contrast, in the higher group, there was significant difference：compared with patients with lingualized occlusal dentures, patients with long centric occlusal dentures had relatively higher masticatory efficiency. Conclusion For patients with high amount of biochemical markers of bone turnover, long centric occlusal dentures are helpful to them to achieve higher masticatory efficiency. Biochemical markers of bone turnover are reasonable to be expected as an index to assess the denture options for edentulous patients with severe residual alveolar ridge resorption.

Key words: long centric occlusal denture, lingualized occlusal denture, biochemical markers of bone turnover, masticatory efficiency, complete dentures, edentulous, alveolar ridge resorption