Theracal LC与MTA用于复杂冠折年轻恒牙活髓切断术的临床对照研究

doi:10.13591/j.cnki.kqyx.2024.10.006

摘要/Abstract

摘要：

目的探讨Theracal LC在复杂冠折年轻恒牙活髓切断术中远期临床效果。方法按照严格的纳入、排除标准收集29例牙外伤青少年患者共33颗患牙(男13例,15颗牙;女16例,18颗牙)。采用临床随机对照研究的方法,将研究对象按照所使用盖髓剂的不同,分为两组,试验组为Theracal LC组(n=17),对照组为MTA组(n=16),同名对侧牙或邻牙作为空白对照组。比较临床症状、临床疗效及影像学检查情况,并对比4年内的随访结果。结果 4年的随访中, MTA组与Theracal LC组临床不适症状在治疗后均有所改善和消失。两组短期(6个月)临床成功率均为100%。MTA组第12个月时临床成功率为93.7%。Theracal LC第12个月及第24个月临床成功率分别为94.1%和88.2%。两组临床疗效组间比较无统计学差异(P>0.05)。MTA组牙冠均发生变色,而Theracal LC组则无变色情况。在影像学方面,Theracal LC组的牙本质桥的形成速度相对快于MTA组,两组远期均可见牙本质桥的形成。Theracal LC组的牙本质桥形态复杂,而MTA组多形成线形均匀牙本质桥。结论 Theracal LC作为盖髓剂临床疗效良好及生物安全性良好,可以作为MTA的代替品之一。

关键词: 年轻恒牙, 活髓切断术, Theracal LC, MTA

Abstract:

Objective To explore the long-term clinical effect of Theracal LC on complicated crown fracture of immature permanent teeth. Methods A total of 33 teeth (13 males,15 teeth; 16 females, 18 teeth) from 29 adolescent patients with complicated crown fracture were collected. In this randomized clinical trial, all the samples were divided into two groups depending on the different pulp capping materials: the experimental group-Theracal LC(n=17) and the control group-MTA(n=16), with the same contralateral or adjacent teeth as blank control group. The treated teeth were evaluated clinically and radiographically at 3, 6, 12, 24, 36, 48 months. Results During the 4-year follow-up, clinical symptoms of all the treated teeth in both groups improved and disappeared. At 6 months, the clinical success rate of both groups was 100%. The clinical success rate was 93.7% at 12 months in the MTA group. The clinical success rates of Theracal LC group at 12 months and 24 months were 94.1% and 88.2%, respectively. There was no statistical difference between the groups in clinical efficacy(P>0.05). The samples of MTA group went black, while Theracal LC group had no discoloration. The formation rate of early-formed dentine bridge in Theracal LC group was relatively faster than that in MTA group. The dentine bridge could be seen in all samples of both groups in the long term. The dentine bridges in Theracal LC group had complex morphology, while the linear uniform was mostly seen in MTA group. Conclusion As a pulp capping agent, Theracal LC has good clinical efficacy and biosafety,and can be used as one of the substitutes for MTA.

Key words: immature permanent tooth, pulpotomy, Theracal LC, MTA

中图分类号:

R781.05

吴翠, 李长顺, 张昕. Theracal LC与MTA用于复杂冠折年轻恒牙活髓切断术的临床对照研究[J]. 口腔医学, 2024, 44(10): 753-758.

WU Cui, LI Changshun, ZHANG Xin. A randomized controlled trial of Theracal LC compared to MTA for pulpotomy in immature permanent teeth with complica-ted crown fracture[J]. Stomatology, 2024, 44(10): 753-758.

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一般情况	分组		P
一般情况	Theracal LC	MTA	P
性别	1.411±0.507	1.563±0.512	0.494
年龄/岁	9.45±0.29	9.37±0.22	0.064
外伤时间/h	12.33±0.94	12.58±0.81	0.061
nolla分期	8.67±0.41	8.50±0.56	0.058