汉族人群睡眠质量与牙周炎进展的相关性研究

doi:10.13591/j.cnki.kqyx.2024.10.008

摘要/Abstract

摘要：

目的通过对睡眠情况和牙周状况进行横断面研究,进一步分析睡眠质量与牙周炎进展的相关性。方法选取2022年6月—2023年10月就诊于南京市第一医院口腔科并符合入选标准的患者100例,按照2018年牙周病和植体周病国际新分类将患者分为牙周炎Ⅰ~Ⅳ期。记录患者一般信息,通过匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)问卷调查了解患者睡眠情况,常规牙周检查记录探诊深度(probing depth,PD)、牙周附着水平(attachment level,AL)、出血指数(bleeding index,BI),血常规检测白细胞数量,统计分析睡眠质量和牙周炎的相关性。结果所有患者的平均PSQI得分为(7.01±3.17)分,平均PD、AL分别为(3.52±0.67)、(3.84±1.58)mm,平均BI为(3.15±1.26)。其中Ⅳ期牙周炎患者的PSQI得分最高;Ⅲ、Ⅳ期牙周炎患者的白细胞计数高于Ⅰ、Ⅱ期患者(P<0.05),睡眠质量差牙周炎患者白细胞计数高于睡眠质量正常的牙周炎患者(P<0.000 1)。以PSQI得分为自变量,牙周炎分期为因变量,调整年龄、性别、吸烟、刷牙频率、白细胞计数后,回归分析得到OR为1.480 2(95%CI:1.248 5~1.755 0)。结论睡眠质量和牙周炎之间存在关联性,睡眠质量差可促进牙周组织炎症的发生发展。

关键词: 匹兹堡睡眠质量指数, 牙周炎, 睡眠障碍

Abstract:

Objective To conduct a cross-sectional study on sleep and periodontal conditions, and further analyze the correlation between sleep disorders and the progression of periodontitis. Methods A total of 100 patients who visited the Department of Stomatology at Nanjing First Hospital from June 2022 to October 2023 and met the inclusion criteria were selected. According to the 2018 International New Classification of Periodontitis and Implant Periodontitis, patients were divided into stages Ⅰ-Ⅳ of periodontitis. General patient information was recorded. A Pittsburgh sleep quality index (PSQI) questionnaire survey was conducted to understand the patient’s sleep status, and routine periodontal examinations were conducted to record probing depth (PD), periodontal attachment level (AL), bleeding index (BI), and blood routine tests were used to measure white blood cell count. The correlation between sleep disorders and periodontitis was statistically analyzed. Results The average PSQI score of all patients was (7.01±3.17) points, with an average PD of (3.52±0.67) mm, an average AL of (3.84±1.58) mm, and an average BI of (3.15±1.26). Among them, patients with stage Ⅳ periodontitis had the highest PSQI score. The white blood cell count of patients with stage Ⅲ and Ⅳ periodontitis was higher than that of patients with stage Ⅰ and Ⅱ (P<0.05), and the white blood cell count of patients with sleep disorders and periodontitis was higher than that of patients with periodontitis without sleep disorders (P<0.000 1). Using PSQI score as the independent variable and periodontitis stage as the dependent variable, after adjusting for age, gender, smoking, brushing frequency, and white blood cell count, regression analysis showed an OR of 1.480 2 (95% CI: 1.248 5-1.755 0). Conclusion There is a correlation between sleep disorders and periodontitis, and sleep disorders can promote the occurrence and development of periodontal tissue inflammation.

Key words: Pittsburgh sleep quality index, periodontitis, sleep disorders

中图分类号:

R781.4

吴程宇, 叶宇, 薛昌敖. 汉族人群睡眠质量与牙周炎进展的相关性研究[J]. 口腔医学, 2024, 44(10): 765-769.

WU Chengyu, YE Yu, XUE Chang’ao. Study on the correlation between sleep disorders and the progression of periodontitis[J]. Stomatology, 2024, 44(10): 765-769.

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项目	Ⅰ期	Ⅱ期	Ⅲ期	Ⅳ期	P
主观睡眠质量	1.19±0.73	1.12±0.70	1.43±0.71	2.12±0.82	<0.001
入睡时间	0.62±0.79	0.85±0.66	1.39±0.92	1.52±0.75	<0.001
睡眠时间	0.54±0.69	0.69±0.72	1.13±0.85	1.32±0.79	0.001
睡眠效率	0.73±0.71	0.81±0.73	1.30±0.55	1.48±0.57	<0.001
睡眠障碍	0.96±0.90	0.92±0.83	1.52±0.58	1.80±0.75	<0.001
催眠药物	0	0	0.09±0.28	0.36±0.84	0.016
日间功能障碍	0.77±0.64	1.08±0.73	1.39±0.57	1.16±0.78	0.023
PSQI	4.81±2.59	5.46±2.53	8.26±2.15	9.76±2.42	<0.001

检测指标	Ⅰ期	Ⅱ期	Ⅲ期	Ⅳ期	P
PD/mm	3.02±0.55	3.43±0.53	3.79±0.49	3.88±0.75	<0.001
AL/mm	1.95±0.51	3.45±0.96	4.44±0.92	5.64±0.76	<0.001
BI	1.55±0.51	2.98±0.92	3.78±0.81	4.40±0.33	<0.001

检查项目	PSQI得分
检查项目	r	P
PD	0.310	0.002
AL	0.490	<0.001
BI	0.499	<0.001
牙周炎分期	0.612	<0.001
白细胞计数	0.506	<0.001