口腔医学 ›› 2024, Vol. 44 ›› Issue (6): 458-461.doi: 10.13591/j.cnki.kqyx.2024.06.011

• 综述 • 上一篇    下一篇

糖尿病影响牙周炎患者口腔龈下菌群和唾液菌群组成的研究进展

林仁杰1,戴安娜2,汪淑华1,丁佩惠2()   

  1. 1 浙江中医药大学口腔医学院,浙江杭州(310000)
    2 浙江大学医学院附属口腔医院,浙江大学口腔医学院,浙江省口腔疾病临床医学研究中心,浙江省口腔生物医学研究重点实验室,浙江大学癌症研究院,浙江杭州(310000)
  • 收稿日期:2023-09-11 出版日期:2024-06-28 发布日期:2024-06-27
  • 通讯作者: 丁佩惠 Tel:(0571)87215797E-mail:phding@zju.edu.cn
  • 基金资助:
    国家自然科学基金(82170953);浙江省重点研发项目领雁计划(2022C03088);浙江大学医学院附属口腔医院探索与研发项目(RD2022DLYB01)

Research progress of the influence of diabetes mellitus on subgingival and salivary flora with periodontitis

LIN Renjie1,DAI Anna2,WANG Shuhua1,DING Peihui2()   

  1. School of Stomatology, Zhejiang Chinese Medical University,Hangzhou 310000, China
  • Received:2023-09-11 Online:2024-06-28 Published:2024-06-27

摘要:

既往研究中,牙周炎和糖尿病的“双向关系”已得到确立。龈下菌群和唾液菌群常被用于研究糖尿病和牙周炎微生物组之间的关系。近年来,测序技术的发展为探究糖尿病对口腔微生物的影响提供了更广阔且深入的途径。本综述旨在对糖尿病影响牙周炎患者口腔龈下菌群和唾液菌群的组成进行阐述,以期为临床上评估伴糖尿病牙周炎提供参考。

关键词: 牙周炎, 糖尿病, 龈下菌群, 唾液菌群, 测序技术

Abstract:

In previous studies, the two-way relationship between periodontitis and diabetes has been established. Subgingival flora and salivary flora are often used to explore the relationship between the microbiome in diabetes and periodontitis. In recent years, the development of sequencing technology has provided a broader and deeper approach to exploring the impact of diabetes on oral microbiome. This review aims to summarize the effects of diabetes on subgingival flora and salivary flora in patients with periodontitis, so as to provide reference for clinical diagnosis and treatment.

Key words: periodontitis, diabetes mellitus, subgingival flora, salivary flora, sequencing technology

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