口腔-肠道微生物轴与呼吸系统疾病关系的研究进展

doi:10.13591/j.cnki.kqyx.2024.12.013

摘要/Abstract

摘要：

微生物群失调与人体中的多种疾病有关,而肠道作为人体内最大的微生物栖息地与口腔的微生物环境密不可分。口腔微生物群可以随着消化系统转移到肠黏膜。同时,肠道至口腔的微生物传播也会以人际和社区传播发生。口腔与肠道之间的微生物传播可以塑造或重塑两个生态环境中的微生物生态系统,最终调节疾病的发病机制。口腔-肠道微生物轴的菌群紊乱会对呼吸系统的相关疾病有重要的影响作用。该文就口腔-肠道微生物紊乱对呼吸系统疾病关系的研究状况作一综述。

关键词: 口腔微生物, 肠道菌群, 呼吸系统疾病

Abstract:

The imbalance of microbiota is related to various diseases in the human body, and the gut, as the largest microbial habitat in the human body, is closely related to the oral microbial environment. The oral microbiota can migrate to the intestinal mucosa with the digestive system. At the same time, microbial transmission from the gut to the mouth can also occur through interpersonal and community transmission. Microbial transmission between the mouth and intestines can shape or reshape the microbial ecosystem in the two habitats, ultimately regulating the pathogenesis of the disease. The dysbiosis of the oral-gut microbiota axis can have a significant impact on related diseases such as respiratory diseases. This article reviews the research status of the relationship between oral-gut microbes and respiratory diseases.

Key words: oral microbiota, intestinal microflora, respiratory diseases

中图分类号:

R780.2

相欢欢, 戴周丽, 张雨菲, 吴嘉文, 韩子慧, 陈锶一. 口腔-肠道微生物轴与呼吸系统疾病关系的研究进展[J]. 口腔医学, 2024, 44(12): 946-951.

XIANG Huanhuan, DAI Zhouli, ZHANG Yufei, WU Jiawen, HAN Zihui, CHEN Siyi. Developments in research on the relationship between oral-gut microbes and respiratory diseases[J]. Stomatology, 2024, 44(12): 946-951.

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