降钙素基因相关肽对牙正畸移动微环境改建作用的研究进展

doi:10.13591/j.cnki.kqyx.2022.01.014

Abstract

Abstract: Calcitonin gene-related peptide (CGRP) is a neuropeptide secreted by nerve endings. In recent years, it has attracted much attention because it has been found to be a key factor in nerve regulation of bone remodeling and is related to the remodeling of blood vessels and collagen fibers. During orthodontic tooth movement (OTM), the remodeling of the local periodontal microenvironment includes alveolar bone, periodontal ligament, gums and also mainly covers nerves, blood vessels, collagen and bone tissues. Exploring the specific mechanism of CGRP regulating nerve, bone, blood vessel, and collagen remodeling is particularly important for understanding the remodeling of microenvironment during orthodontic movement, but the specific mechanism is not yet fully understood. This article reviews its research progress.

Key words: calcitonin gene-related peptide, orthodontic tooth movement, organizational remodeling

CLC Number:

R783.5

JI Yaning, QIAN Suting, DING Lingmin, LIN Jun. Research progress of the effect of calcitonin gene-related peptide on the microenvironment reconstruction of orthodontic tooth movement[J]. Stomatology, 2022, 42(1): 79-83.

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Research progress of the effect of calcitonin gene-related peptide on the microenvironment reconstruction of orthodontic tooth movement

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