Abstract: Objective To compare the application of iRoot BP Plus and inorganic trioxide polymer (MTA) in immature permanent teeth with pulp revascularization. Methods A total of 100 patients (100 teeth) with pulp revascularization in our hospital were selected. According to the use of filling materials, there were 50 cases in MTA group (50 teeth, 2 cases lost to follow-up) and 50 cases in iRoot BP Plus group (50 teeth, 1 case lost to follow-up). The root development, root canal wall thickness and root length, old periapical index (O-PAI) changes at different time, clinical efficacy and complications were compared between the two groups. Results The developmental typing of iRoot BP Plus group was better than MTA group (χ²=2.21,P<0.05); the measurement results of root canal wall thickness, root length and growth rate in iRoot BP Plus group were higher than those in MTA group (t=3.511, 3.342, 9.983, 10.638, P<0.05). The O-PAI rating of iRoot BP Plus group at 12 months and 24 months was lower than that of MTA group (t=8.570, 8.268, P<0.05). The total effective rates of MTA group and iroot BP plus group were 89.80% and 97.96% respectively, and the difference was statistically significant (χ²=4.461,P<0.05). The incidence of complications in MTA group and iRoot BP Plus group were 32.65% and 6.12% respectively, with significant difference (χ²=20.854,P<0.05). Conclusion iRoot BP Plus has better effect than MTA on immature permanent teeth with pulp revascularization. Moreover, it is more conducive to root development and control of complications.

Key words: immature permanent tooth, revascularization, iRoot BP Plus, MTA