3D打印个性化钛网引导种植区骨再生的临床并发症研究

doi:10.13591/j.cnki.kqyx.2022.03.011

Abstract

Abstract: Objective To evaluate the effect of a modified guided bone regeneration technique on reducing the incidence of complications during bone healing based on 3D printing personalized titanium mesh technology. Methods From September 2019 to July 2021, 9 patients aged 45.6±8.0 with severe residual alveolar bone deficiency (9 bone graft areas and 24 denture sites) were enrolled in the Department of Stomatology, the First Affiliated Hospital of Dalian Medical University. Implants were simulated in the software guided by prosthetics and biology, then the personalized titanium mesh was designed and manufactured by 3D printing. Intraoperatively, the bone graft material was overfilled with 1 mm based on the profile of the personalized titanium mesh, and then the absorbable collagen membrane was covered on the surface to fix the bone graft material. Guided bone regeneration surgery was completed for 9 patients. During postoperative healing, 9 patients were observed for incision dehiscing, titanium mesh exposure, surrounding soft tissue infection and the formation of “pseudoperiosteum” at the bone graft site. Results ①Temporary skin numbness in mental region occurred in 1 of 9 patients, which was relieved at the 6^th month and almost disappeared at the 9^th month. ②14 days after surgery, two patients were found to have wound edge dehashes of about 2 mm during suture removal, and only absorbable collagen membrane was exposed, but titanium mesh was not exposed, and no infection occurred. The soft tissue healed at the follow-up visit 1 month after surgery. ③During the follow-up of 1 to 9 months after surgery, no complications such as soft tissue dehiscing, titanium mesh exposure and infection were observed in all patients. ④No obvious formation of fibrous connective tissue, namely “pseudoperiosteum”, was observed on the surface of all grafts after the titanium mesh was removed. Conclusion In the application of 3D printed personalized titanium mesh technology to guide bone regeneration, an excessive bone graft implantation combined with absorbable collagen membrane covering can double isolate the direct contact between titanium mesh and mucous membrane, and can effectively reduce complications such as incision dehashes, titanium mesh exposure and infection.

Key words: 3D printed personalized titanium mesh, guided bone regeneration, titanium mesh exposure

CLC Number:

R783.4

DENG Lei, LEI Yuchen, CHEN Gang, WANG Chao, HUANG Haitao. Clinical study on complications of bone regeneration guided by 3D printed personalized titanium mesh in implanting area[J]. Stomatology, 2022, 42(3): 244-249.

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Clinical study on complications of bone regeneration guided by 3D printed personalized titanium mesh in implanting area

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