Stomatology ›› 2022, Vol. 42 ›› Issue (6): 540-544.doi: 10.13591/j.cnki.kqyx.2022.06.011

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Progress of research on mechanism of β-arrestin 2 regulating inflammatory disease

FENG Meiting, LUO Lijun   

  1. Department of Periodontics, School of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072,China
  • Revised:2021-12-07 Online:2022-06-28 Published:2022-07-21

Abstract: β-arrestin 2 belongs to the inhibitory protein family which plays a pivotal role in inflammatory diseases, and it involves in inflammatory diseases through the G protein-coupled receptor(GPCR) signal transduction pathway and its participation in various signaling pathways. In this paper we review the function of β-arrestin 2 and summarize the mechanism of β-arrestin 2 in inflammatory diseases.

Key words: β-arrestin 2, inflammatory disease, G protein-coupled receptor

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