Stomatology ›› 2022, Vol. 42 ›› Issue (6): 551-556.doi: 10.13591/j.cnki.kqyx.2022.06.013

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Antibacterial mechanism and influencing factors of bioactive glasses

DONG Junchi, ZHENG Huiling, WEI Yuwen, MA Qian   

  1. Department of General Dentistry, Affiliated Stomatological Hospital of Nanjing Medical University; Jiangsu Province Key Laboratory of Oral Diseases; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing 210029, China
  • Revised:2021-10-03 Online:2022-06-28 Published:2022-07-21

Abstract: Bioactive glasses(BGs) are bioactive materials based on the SiO2-Na2O-CaO-P2O5 oxide system. They have good osteogenic activity, antibacterial activity and biocompatibility. BGs have significant antibacterial effects on common oral bacteria in clinic and will not lead to drug resistance. Thus, BGs have application prospects as oral bacteriostatic agents. However, there is no conclusive research on its antibacterial mechanism. This article reviews the antibacterial effects and mechanisms of BGs on common oral pathogens and summarizes its influencing factors.

Key words: bioactive glasses(BGs), antibacterial mechanism, oral bacteriostatic agent

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