口腔癌的侵袭前缘及外科根治策略

doi:10.13591/j.cnki.kqyx.2022.11.001

Abstract

Abstract: Radical resection isthe key for treatment of oral cancer. Depth of invasion, tumour budding and the tumour microenvironment define the biological characteristics of cells in tumor invasive front, thereby determining invasion and metastasis capabilities. Compartmental resection is an important method for oral cancer treatment. Through analysis and review of the cutting-edge research on tumor invasive front, this paper sheds light on optimal radical resection for oral cancer.

Key words: oral cancer, tumor invasive front, depth of invasion, compartmental resection

CLC Number:

R782
R739.85

ZHANG Chenping, WANG Lei. Tumor invasive front of oral cancer and radical surgery strategies[J]. Stomatology, 2022, 42(11): 961-965.

References

[1] Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2022[J]. CA Cancer J Clin, 2022, 72(1):7-33.
[2] 郑荣寿, 陈万青. 癌症发病年龄变化分析[J]. 中华预防医学杂志, 2018, 52(6):673-674.
[3] Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018, 68(6):394-424.
[4] 张志愿. 口腔颌面外科学[M]. 8版.北京:人民卫生出版社, 2020.
[5] 丁洁, 韩伟, 孙国文. 第八版美国癌症联合委员会唇与口腔肿瘤TNM分期更新解读[J]. 中华口腔医学杂志, 2017, 52(8):504-509.
[6] Lugli A, Kirsch R, Ajioka Y, et al. Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016[J]. Mod Pathol, 2017, 30(9):1299-1311.
[7] Sarioglu S, Acara C, Akman FC, et al. Tumor budding as a prognostic marker in laryngeal carcinoma[J]. Pathol Res Pract, 2010, 206(2):88-92.
[8] Karamitopoulou E, Zlobec I, Born D, et al. Tumour budding is a strong and independent prognostic factor in pancreatic cancer[J]. Eur J Cancer, 2013, 49(5):1032-1039.
[9] Liang FL, Cao W, Wang YL, et al. The prognostic value of tumor budding in invasive breast cancer[J]. Pathol Res Pract, 2013, 209(5):269-275.
[10] Kadota K, Yeh YC, Villena-Vargas J, et al. Tumor budding correlates with the protumor immune microenvironment and is an independent prognostic factor for recurrence of stage I lung adenocarcinoma[J]. Chest, 2015, 148(3):711-721.
[11] Gujam FJA, McMillan DC, Mohammed ZMA, et al. The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer[J]. Br J Cancer, 2015, 113(7):1066-1074.
[12] Almangush A, Pirinen M, Heikkinen I, et al. Tumour budding in oral squamous cell carcinoma:A meta-analysis[J]. Br J Cancer, 2018, 118(4):577-586.
[13] Xie N, Wang C, Liu XQ, et al. Tumor budding correlates with occult cervical lymph node metastasis and poor prognosis in clinical early-stage tongue squamous cell carcinoma[J]. J Oral Pathol Med, 2015, 44(4):266-272.
[14] 张士剑. IL-17-STAT3通路调控口腔鳞癌侵袭力及临床相关性研究[D]. 上海:上海交通大学, 2019.
[15] Leão PLR, Marangon Junior H, Melo VVM, et al. Reproducibility, repeatability, and level of difficulty of two methods for tumor budding evaluation in oral squamous cell carcinoma[J]. J Oral Pathol Med, 2017, 46(10):949-955.
[16] Xu S, Cao XT. Interleukin-17 and its expanding biological functions[J]. Cell Mol Immunol, 2010, 7(3):164-174.
[17] Miyahara Y, Odunsi K, Chen WH, et al. Generation and regula-tion of human CD4⁺ IL-17-producing T cells in ovarian cancer[J]. Proc Natl Acad Sci USA, 2008, 105(40):15505-15510.
[18] Zhang JP, Yan J, Xu J, et al. Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients[J]. J Hepatol, 2009, 50(5):980-989.
[19] Zhuang Y, Peng LS, Zhao YL, et al. CD8(+) T cells that produce interleukin-17 regulate myeloid-derived suppressor cells and are associated with survival time of patients with gastric cancer[J]. Gastroenterology, 2012, 143(4):951-962.e8.
[20] Jiang YX, Yang SW, Li PA, et al. The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms[J]. Oncogene, 2017, 36(9):1256-1264.
[21] Lee JJ, Chang YL, Lai WL, et al. Increased prevalence of interleukin-17-producing CD4(+) tumor infiltrating lymphocytes in human oral squamous cell carcinoma[J]. Head Neck, 2011, 33(9):1301-1308.
[22] Kesselring R, Thiel A, Pries R, et al. Human Th17 cells can be induced through head and neck cancer and have a functional impact on HNSCC development[J]. Br J Cancer, 2010, 103(8):1245-1254.
[23] Gu FM, Li QL, Gao Q, et al. IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma[J]. Mol Cancer, 2011, 10:150.
[24] Warnakulasuriya S. Living with oral cancer:Epidemiology with particular reference to prevalence and life-style changes that influence survival[J]. Oral Oncol, 2010, 46(6):407-410.
[25] 张陈平. 舌癌的间室外科[J]. 中国癌症杂志, 2013, 23(12):937-941.
[26] Ong HS, Ji T, Zhang CP. Resection for oral tongue squamous cell carcinoma:A paradigm shift from conventional wide resection towards compartmental resection[J]. Int J Oral Maxillofac Surg, 2014, 43(6):784-786.
[27] Sutton DN, Brown JS, Rogers SN, et al. The prognostic implications of the surgical margin in oral squamous cell carcinoma[J]. Int J Oral Maxillofac Surg, 2003, 32(1):30-34.
[28] Patel RS, Goldstein DP, Guillemaud J, et al. Impact of positive frozen section microscopic tumor cut-through revised to negative on oral carcinoma control and survival rates[J]. Head Neck, 2010, 32(11):1444-1451.
[29] Comen E, Norton L, Massagué J. Clinical implications of cancer self-seeding[J]. Nat Rev Clin Oncol, 2011, 8(6):369-377.
[30] Han W, Yang XD, Huang XF, et al. Metastases to lingual lymph nodes from squamous cell carcinoma of the tongue[J]. Br J Oral Maxillofac Surg, 2008, 46(5):376-378.
[31] Dutton JM, Graham SM, Hoffman HT. Metastatic cancer to the floor of mouth:The lingual lymph nodes[J]. Head Neck, 2002, 24(4):401-405.
[32] Ong HS, Gokavarapu S, Tian Z, et al. Does a mandibular access osteotomy improve survival in PT2 oral tongue cancers? Retrospective study at a single institution[J]. Int J Oral Maxillofac Surg, 2018, 47(3):289-295.
[33] Jerjes W, Upile T, Petrie A, et al. Clinicopathological parameters, recurrence, locoregional and distant metastasis in 115 T1-T2 oral squamous cell carcinoma patients[J]. Head Neck Oncol, 2010, 2:9.
[34] 夏超, 吕俊, 谭颖徽. 间室切除术在舌癌手术治疗中的临床应用[J]. 临床口腔医学杂志, 2020, 36(1):43-45.
[35] Lydiatt WM, Patel SG, O'Sullivan B, et al. Head and Neck cancers-major changes in the American Joint Committee on cancer eighth edition cancer staging manual[J]. CA Cancer J Clin, 2017, 67(2):122-137.
[36] Ebrahimi A, Luk PP, Low H, et al. The American Joint Committee on Cancer staging for metastatic head and neck cutaneous squamous cell carcinoma:A multi-institutional study of within-stage heterogeneity and impact on prognostic performance[J]. Head Neck, 2020, 42:3235-3242.
[37] Caudell JJ, Gillison ML, Maghami E, et al. NCCN Guidelines^® Insights:Head and Neck Cancers, Version 1.2022[J]. J Natl Compr Canc Netw, 2022, 20(3):224-234.
[38] D'Cruz AK, Vaish R, Kapre N, et al. Elective versus therapeutic neck dissection in node-negative oral cancer[J]. N Engl J Med, 2015, 373(6):521-529.
[39] Civantos FJ, Zitsch RP, Schuller DE, et al. Sentinel lymph node biopsy accurately stages the regional lymph nodes for T1-T2 oral squamous cell carcinomas:Results of a prospective multi-institutional trial[J]. J Clin Oncol, 2010, 28(8):1395-1400.
[40] 刘剑楠, 胡俊磊, 韩婧, 等. 基于智能术前规划的下颌骨重建手术机器人系统实验验证[J]. 中华整形外科杂志, 2021,37(2):130-136.
[41] 张陈平, 刘剑楠. 颌面肿瘤毁容貌,修复重建塑尊严口腔颌面部修复重建外科的历史、现状及未来 [J]. 中华整形外科杂志, 2021, 37(2):125-129.
[42] 张陈平. 口腔颌面-头颈肿瘤的诊治与整合医学[J]. 中华口腔医学杂志, 2017, 52(8):465-469.
[43] 邱蔚六. 邱蔚六口腔颌面外科学[M]. 上海:上海科学技术出版社, 2008.
[44] Ferris RL, Flamand Y, Weinstein GS, et al. Phase Ⅱ randomized trial of transoral surgery and low-dose intensity modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer:An ECOG-ACRIN cancer research group trial (E3311)[J]. J Clin Oncol, 2022, 40(2):138-149.

Tumor invasive front of oral cancer and radical surgery strategies

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[3]	. Recombinant human lactoferrin inhibits proliferation and induces apoptosis in oral cancer KB cells [J]. , 2018, 38(9): 785-790.
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