Stomatology ›› 2024, Vol. 44 ›› Issue (10): 786-790.doi: 10.13591/j.cnki.kqyx.2024.10.012

• Review • Previous Articles     Next Articles

Application of Raman spectroscopy in the identification of oral bacteria

QI Linlong,QIN Zirui,TENG Jianying,ZHANG Shuyang,WANG Yuan,DENG Shuli()   

  1. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou 310000, China
  • Received:2023-12-14 Online:2024-10-28 Published:2024-10-23

Abstract:

Oral bacteria are associated with a variety of oral diseases such as caries, periodontal disease and oral cancer. Some pathogenic bacteria also play an important role in the occurrence and development of systemic diseases. The rapid identification of bacterial pathogens helps the diagnosis and precise treatment of oral diseases. Raman spectroscopy is a simple, rapid and non-invasive novel detection technique that can provide abundant and detailed bacterial information and can rapidly identify bacteria, but the application of this technique in oral clinical settings is still relatively rare and needs further exploration. This paper summarizes the research progress of Raman spectroscopy in the identification of oral bacteria and discusses the prospects and challenges of its clinical application.

Key words: Raman spectroscopy, oral microbiota, oral pathogens

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