Stomatology ›› 2025, Vol. 45 ›› Issue (9): 713-720.doi: 10.13591/j.cnki.kqyx.2025.09.013

• Review • Previous Articles    

Application of glucocorticoids in oral mucosal diseases

YING Minqian, LI Kaiyue, LIU Chuanxia()   

  1. Oral Medicine,Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou 310000, China
  • Received:2024-08-21 Online:2025-09-28 Published:2025-09-11

Abstract:

Glucocorticoids possess potent anti-inflammatory and immunosuppressive properties, rendering them a common therapeutic option for oral mucosal diseases. The mechanisms of glucocorticoid action are diverse, encompassing both genomic and non-genomic effects. Given the ubiquitous presence of glucocorticoid receptors in nearly all human cells, their impact is widespread. While the efficacy of glucocorticoids is evident, prolonged or high-dose administration can lead to various adverse effects. Therefore, it is crucial to understand the mechanism of action and adverse reactions of glucocorticoids, master the indications and dosage of glucocorticoids in the treatment of oral mucosal diseases, and apply glucocorticoids correctly and reasonably in the diagnosis and treatment of oral mucosal diseases. At the same time, it is important to monitor the adverse reactions after medication and deal with them timely to ensure the safety of medication for patients.

Key words: glucocorticoids, oral mucosal diseases, action mechanism, efficacy, adverse reactions

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