Abstract: Abstract： Objective The aim of this study was to compare the clinical performance of glass-fiber posts in combination with either self-adhesive resin cements or self-etch adhesives over up to 3 years in restoration of teeth. Methods 220 premolar teeth and anterior teeth (from 100 cases) that needed post-core crown restoration were allocated into 2 groups randomly. Group A were restored with glass fiber posts in combination with self-adhesive resin cements. Group B were restored with glass fiber posts in combination with self-etch adhesives. Two groups were restored with porcelain fused metal crowns or full-ceramic crowns. The success rates of two groups were observed 36 months later. The data was statistically analyzed by χ2 test. Results 103 teeth (from 46 cases) in group A and 98 teeth (from 48 cases) in group B were evaluated after 36 months. There was no fiber post fracture, root fracture, and post debonding in group A. Its success rate was 100%. There was one post debonding and no root fracture or fiber post fracture In group B. Its success rate was 98.99%. The difference in the success rates between two groups was no statistically significant. Conclusion In fiber post-core restoration, clinical performance of glass-fiber posts in combination with either self-adhesive resin cements or self-etch adhesives was favorable.