›› 2016, Vol. 36 ›› Issue (10): 950-952.

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Research progress of the mechanism and function of primary cilium on tooth development

Chen-Yang ZHANG,   

  • Received:2016-05-17 Revised:2016-06-23 Online:2016-10-28 Published:2016-10-25

Abstract: Abstract: The primary cilium is a specialized cellular process of mammalian cells. With a large amount of cell signal molecules in it, the primary cilium forms a large information system in cells. Recently, primary cilium has been found in tooth forming cells, and it is reported that dysfunction of cilium can cause dysplasia of teeth,which suggests primary cilium is involved in tooth development. In order to demonstrate the function and signaling pathways of the cilium in tooth development, research on the mechanism and function of primary cilium will be reviewed. It may broaden our understanding of the molecular mechanisms underlying tooth development.

Key words: Primary Cilium, Tooth development, Hh signaling, Wnt signaling

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