Stomatology ›› 2022, Vol. 42 ›› Issue (3): 261-265.doi: 10.13591/j.cnki.kqyx.2022.03.014

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Role of biologics in the treatment of oral lichen planus

SUN Yutong, JIANG Lu   

  1. Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University;State Key Laboratory of Oral Diseases;National Clinical Research Center for Oral Diseases, Chengdu 610041, China
  • Revised:2021-09-10 Online:2022-03-28 Published:2022-03-21

Abstract: Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology, and is closely related to autoimmunity. Corticosteroids and immunosuppressants are commonly used drugs for OLP treatment, but some OLP patients show insensitivity or treatment resistance. Research suggests that biologics have advantages for OLP patients that are not sensitive or are resistant to conventional drug treatment. This article reviews the types, mechanisms, efficacy, prognosis, and adverse reactions of biologics for OLP treatment and provides references for the treatment of OLP.

Key words: oral lichen planus, biologics, treatment

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