病毒感染相关天疱疮

doi:10.13591/j.cnki.kqyx.2023.09.016

Abstract

Abstract:

Pemphigus is a group of autoimmune bullous diseases that can affect skin and mucosa. The etiology mainly includes genetic susceptibility and environmental factors. As one of the critical environmental factors, virus infection is considered to be closely related to the occurrence of pemphigus. Herpes simplex virus, hepatitis virus, and other viral infections may all trigger pemphigus. The potential mechanism involves molecular mimicry, continuous formation of antigen-antibody immune complexes, and abnormal differentiation and function of T cell subsets. Pemphigus patients with viral infection may benefit from combining conventional glucocorticoid or immunosuppressive therapy and antiviral therapy. This article reviews the relationship between viral infection and pemphigus, the potential pathogenic mechanism, and the selection of clinical treatment options for viral infection-related pemphigus.

Key words: pemphigus, pemphigus vulgaris, viral infection, autoimmune, antiviral therapy

CLC Number:

R781.53

ZHOU Hangfan, JIANG Lu. Viral infection-related pemphigus[J]. Stomatology, 2023, 43(9): 854-860.

Figures/Tables 2

References 82

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