Abstract:

Objective To evaluate the contributions of resveratrol to dentin biomimetic remineralization and resin-dentin bond durability. Methods The middle dentin slices cut by a low-speed diamond saw were etched with 35% phosphoric acid and divided into three groups, which were respectively immersed in distilled water(Ctr group), directly remineralized for 7 d (Pos group), and pretreated with resveratrol for 30 min and then remineralized for 7 d (Res group). The formation of minerals on the dentin surface was observed by scanning electron microscope(SEM), and the crystal characteristics were analyzed by X-ray diffraction(XRD)and attenuated total reflection Fourier transform infrared spectroscopy(ATR-FTIR). Micro tensile strength was used to observe the resin-dentin bond durability. Results SEM showed that the dentin after remineralization could form crystals, and more crystals were formed on the resveratrol-pretreated dentin surface. XRD and ATR-FTIR analysis showed that the newly formed crystal was hydroxyapatite(HA). Pretreatment with resveratrol significantly increased the initial micro-tensile strength compared with the positive control group without primer conditioning. Micro-tensile strength decreased during aging, however, the decrease in resveratrol-pretreated samples was the least significant. Conclusion Resveratrol can promote the biomimetic remineralization of demineralized dentin and improve resin-dentin bond durability.

Key words: resveratrol, dentin, biomimetic remineralization, resin-dentin bond durability