Stomatology ›› 2025, Vol. 45 ›› Issue (9): 701-706.doi: 10.13591/j.cnki.kqyx.2025.09.011

• Review • Previous Articles     Next Articles

Research progress of biomimetic wet-adhesive hydrogel in oral dressings

DING Shuwen, ZHU Jiayu, ZHAO Jiechen, WU Xiaohua, WU Junhua()   

  1. Department of Prosthodontics, Shanghai Tongji Stomatological Hospital and Dental School, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology, Shanghai 200072, China
  • Received:2024-11-26 Online:2025-09-28 Published:2025-09-11

Abstract:

Biomimetic wet-adhesive hydrogels mimic the adhesive properties of biological organisms to achieve strong bonding in moist environments. Compared to conventional medical adhesives, these materials are characterized by enhanced biocompatibility, robust adhesion, and adjustable physicochemical properties. Although biomimetic wet-adhesive hydrogels have been applied in oral mucosal drug delivery, intraoral wound management, and implant surgery, a systematic review is currently lacking. This article aims to summarize the wet-adhesion mechanisms of bio-inspired materials and their applications in various scenarios and to provide insights and methodologies for the design of novel intraoral dressings.

Key words: biomimetic material, wet-adhesives, mussel, octopus sucker, barnacle cement

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