Stomatology ›› 2025, Vol. 45 ›› Issue (9): 696-700.doi: 10.13591/j.cnki.kqyx.2025.09.010

• Review • Previous Articles     Next Articles

Research progress of the relationship between macrophages and periodontitis

HAO Yandi1,2, LIU Ye1, GAO Pengyu3, YANG Jingshu1,2, XU Quanchen1,2()   

  1. Department of Stomatology, Affiliated Hospital of Qingdao University,Qingdao 266003,China
  • Received:2024-12-10 Online:2025-09-28 Published:2025-09-11

Abstract:

Periodontitis is a common chronic infectious disease resulting from the interaction between oral microorganisms and the host’s immune system. The immune system plays a dual role in regulating inflammation. Macrophages, as a component of innate immunity, play a crucial role in both the onset and resolution of periodontitis. This article reviews the role of macrophages in periodontitis and the recent advances in targeting macrophages for the treatment of periodontitis.

Key words: periodontitis, macrophages, immune regulation

CLC Number: